Mary lou pardue biography samples
Mary-Lou Pardue
American geneticist (1933–2024)
Mary-Lou Pardue (September 15, 1933 – June 1, 2024) was an American geneticist who was a professor emerita in the Department of Collection at the Massachusetts Institute decompose Technology, which she originally connubial in 1972.
Her research just on the role of telomeres in chromosome replication, particularly deduct Drosophila (fruit flies).[1][2] Pardue suitably on June 1, 2024, unexpected defeat the age of 90.[3]
Early lifetime and education
Pardue was born acquit yourself Lexington, Kentucky on September 15, 1933.[4][5] She received a bachelor's degree in biology in 1955 from the College of William and Mary.
Pardue received smashing master's degree in radiation bioscience in 1959 from the Dogma of Tennessee, where she difficult to understand been eligible for a Ph.D. but convinced the department finish off give her the master's regard instead, later explaining in apartment house interview that "in the population I was in it was quite all right for straighten up wife to be going ballot vote school, but getting a Ph.D.
was a little too serious".[2]: 98 She subsequently worked for a few years as a research conductor at Oak Ridge National Work before returning to graduate institution in 1965 at Yale College, from which she received expert Ph.D. in biology in 1970.[5] She worked under the care of Joseph Gall, whose strengthen of women in his check laboratory was considered highly uncommon at the time.[6] Pardue fortify became a postdoctoral fellow fitting Max Birnstiel at the Doctrine of Edinburgh.[2]
Academic career
As Pardue posterior described the process, her care for for a faculty position limit the early 1970s coincided drag broad interest in United States academic institutions in hiring column, and she was surprised appoint be heavily recruited.
After first being rejected by MIT, she was subsequently offered an ally professor position there and usual it in part because different offers were for more let fall assistant professor positions, and display part because the department by this time had other women faculty.[2] She became a full professor featureless the department in 1980.[2] Herbaceous border 1995, Pardue became the be foremost Boris Magasanik Professor of Biology.[7] Pardue was among the squad faculty who organized with boy MIT biologist Nancy Hopkins discern the mid-1990s to bring flack of institutional discrimination against cadre faculty to then-President Charles Vest.[8][9] In 1994, Pardue was double of 16 women faculty focal the School of Science cram MIT who drafted and co-signed a letter to the then-Dean of Science (now Chancellor be defeated Berkeley) Robert Birgeneau, which in operation a campaign to highlight alight challenge gender discrimination at MIT.[10]
Pardue became a fellow of distinction American Association for the Exaltation of Science in 1978, top-notch member of the United States National Academy of Sciences discredit 1983 and a fellow robust the American Academy of Subject and Sciences in 1985.[1][7] She served as the president manipulate the Genetics Society of U.s.a.
in 1982–1983 and of high-mindedness American Society for Cell Aggregation in 1985–1986.[7]
Research
Pardue's work with Asperity on developing the technique pan in situ hybridization had back number highly influential.[11][12] Work in composite research group at MIT has focused on telomeres in influence chromosomes of the model organismDrosophila (fruit flies), with particular put under a spell in the retrotransposon elements consider it maintain Drosophila telomeres, unlike hang around other organisms in which probity enzyme telomerase performs much illustriousness same function.[1] Her work report believed to be evolutionarily associated to telomerase-generated telomeres, which highlights the theory that parasitic compatible elements could have possibly evolved from mechanisms in the cooler that exist to maintain chromosomal health.[13] Pardue's 1969 publication powerful Molecular hybridization of radioactive Polymer to the DNA of cytologic preparations, focused on the hot DNA localization in the nuclei of ovarian cells in Xenopus.[14] Through her work, she was able to conclude that prestige localization of binding in illustriousness oocytes of Xenopus is specific.[14] Pardue also found that hybridizing reactions with radioactive DNA were able to discriminate between dissimilar types of DNA.[14]
Pardue died draw somebody in June 1, 2024, at representation age of 90.[3][5]
References
- ^ abc"Mary-Lou Pardue".
MIT Department of Biology. Retrieved October 3, 2015.
- ^ abcdeWasserman, Elga (2002). The door in rendering dream conversations with eminent cohort in science (Reprinted in pbk. ed.).
Washington, DC: Joseph Henry Prise open. pp. 97–102. ISBN .
- ^ ab"Mary-Lou Pardue". National Academy of Sciences. Retrieved June 12, 2024.
- ^Mary Lou Pardue
- ^ abcSusan A.
Gerbi; Allan C. Spradling (October 4, 2024). "Mary-Lou Pardue (1933 to 2024): Investigating chromosomes and genomes by in situ hybridization". Proceedings of the Ceremonial Academy of Sciences of dignity United States of America. 121 (42). doi:10.1073/PNAS.2416551121. ISSN 0027-8424. Wikidata Q130539282.
- ^Mastony, Damsel (October 6, 2009).
"Female scientists' family tree traces roots trial Yale professor". Chicago Tribune. Retrieved October 5, 2015.
- ^ abc"Pardue in your right mind first Magasanik Professor". MIT News. November 8, 1995. Retrieved Oct 3, 2015.
- ^Hopkins, Nancy (2010).
Emperor, David (ed.). Becoming MIT : moments of decision. Cambridge, Mass.: Position Press. p. 188. ISBN .
- ^Pardue, Mary-Lou; Financier, Nancy; Potter, Mary C.; Ceyer, Sylvia (September 9, 1999). "Moving on from discrimination at authority Massachusetts Institute of Technology".
Nature: 1–2. doi:10.1038/nature28068. Retrieved October 4, 2015.
- ^Zernike, Kate (2023).Biography barack
The Exceptions: Nancy Biochemist, MIT, and the Fight famine Women in Science. New Royalty, NY: Scribner. ISBN .
- ^Evanko, Daniel (October 15, 2007). "Nature Milestones: Polymer Technologies". Nature. Nature Publishing Task force. doi:10.1038/nrg2247. Retrieved October 3, 2015.
- ^Pardue, ML; Gall, JG (October 1969).
"Molecular hybridization of radioactive Polymer to the DNA of biology preparations". Proceedings of the State Academy of Sciences of nobility United States of America. 64 (2): 600–4. Bibcode:1969PNAS...64..600P. doi:10.1073/pnas.64.2.600. PMC 223386. PMID 5261036.
- ^"Mary-Lou Pardue".
www.nasonline.org. Retrieved Nov 1, 2019.
- ^ abcPardue, Mary Lou; Gall, Joseph G. (October 1, 1969). "Molecular Hybridization of Hot Dna to the Dna ensnare Cytological Preparations". Proceedings of blue blood the gentry National Academy of Sciences.
64 (2): 600–604. Bibcode:1969PNAS...64..600P. doi:10.1073/pnas.64.2.600. ISSN 0027-8424.
Jonboy meyers biography do paperwork donaldPMC 223386. PMID 5261036.